There are two calibration matrices included with UVIS PDS data. The first is a two-dimensional matrix that is of the same spectral and spatial size as the data. In most situations, a single detector readout can be calibrated by multiplying by this matrix. The second calibration matrix included represents that which would be required for an equivalent observation with no binning or windowing (full detector readout), and therefore always has a dimension of 1024x64. The following text describes the situation in which this second calibration matrix may be required. The UVIS FUV detector has pixels whose performance is not well understood. These anomalous pixels are distributed across the entire detector. The calibration approach adopted by most of the UVIS team is to eliminate these detector elements from analysis by setting calibration values to not-a-number (NaN). Applying the calibration matrix to the data will have the effect of forcing these anomalous pixels to also have a value of NaN. One method of dealing with such an irregular array is to interpolate across these spurious pixels. When binning is used, any binned pixel in the calibration matrix will assume a value of NaN if any of its constituent pixels were of that value. In certain circumstances of high binning, most (if not all) of the resulting calibration matrix will have a value of NaN. In such situations, a modified approach to that outlined above is required to retrieve a meaningful measurement. One method is to interpolate across NaN values in the supplied unbinned calibration matrix, bin and window the matrix to match the data, and then apply the matrix to arrive at a calibrated data product. A multiplicative adjustment of 1.1 is then required to account for the effect of including the anomalous pixels in the data.